Human IGF1, 1 mg

Human IGF1, 1 mg

IBP1; IGF1; IGF-1; IGF1A; IGFI; IGF-I; IGF-IA; IGF-IB; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor 1; insulin-like growth factor I; insulin-like growth factor IA; insulin-like growth factor IB; Mechano growth factor; MGF; Somatomedin A; Somatomedin C; somatomedin-C

$250.00

Insulin-like growth factor I (IGF-I or IGF-1), also known as somatomedin C is synthesized as two precursor isoforms with N- and alternate C terminal propeptides. IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally. IGF-I regulates glucose and fatty acid metabolism, steroid hormone activity, and cartilage and bone metabolism. It plays an important role in muscle regeneration and tumor progression. IGF-I/IGF-1 binds IGF-I R, IGF-II R, and the insulin receptor, although its effects are mediated primarily by IGF-I R. The IGF-I protein associates with IGF binding proteins thereby increasing its plasma half life and modulating its interactions with receptors.

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