Mouse TPO, 10 ug
Mouse TPO, 10 ug
Megakaryocyte colony-stimulating factor; Megakaryocyte growth and development factor; megakaryocyte stimulating factor; MGDF; MGDFC-mpl ligand; MKCSF; MK-CSF; ML; MPL ligand; MPLLG; MPLLGMGC163194; Myeloproliferative leukemia virus oncogene ligand; THCYT1; THPO; thrombopoietin nirs variant 1; Thrombopoietin; Tpo; TPOMKCSF
$360.00
Tpo (thrombopoietin) is a key regulator of megakaryocytopoiesis and thrombopoiesis. It primarily produced in the liver and is bound and internalized by the receptor Tpo R/c-mpl. Defects in the Tpo-Tpo R signaling pathway are associated with a variety of platelet disorders. Tpo promotes the differentiation, proliferation, and maturation of MK and their progenitors; in addition, Tpo promotes platelet production, aggregation, ECM adhesion, and activation (1,2).
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