Human THY1 Recombinant Protein (HEK293 Expression)
Price range: $82.00 through $1,500.00
Overview
Thy1 is a glycoprotein that mediates cellular adhesion and exerts a wide range of effects in different tissues. It is expressed on hematopoietic progenitor cells, lymphoid cells, neurons, and activated vascular endothelial cells, and it can form dimers and higher order multimers. Thy1 binds to heparin, the proteoglycan Syndecan-4, and Integrins alpha M beta 2, alpha V beta 3, and alpha V beta 5, inhibiting neurite outgrowth, and promoting astrocyte adhesion, mediating the adhesion and extravasation of leukocytes and melanoma cells, supporting the Thrombospondin-1 induced disassembly of fibroblast focal adhesions, and inhibiting the activation of latent TGF-beta 1, myofibroblast differentiation, and lung fibrosis (1-5).
Quality Assurance
Each lot is tested for purity (SDS-PAGE, SEC-HPLC), endotoxin levels (LAL method), and bioactivity. A Certificate of Analysis (COA) is provided with every order.
Safety Data Sheets & Documentation
Protocols & Support
Reconstitution Protocol
1. Briefly centrifuge the vial to collect lyophilized powder at the bottom.
2. Reconstitute in sterile deionized water or PBS to a concentration of 0.2–1.0 mg/mL.
3. Gently pipette up and down to dissolve. Do not vortex.
4. Aliquot and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
Download Data Sheet
Complete product data sheet including batch-specific QC data, sequence information, and storage guidelines.
Download PDF Data Sheet
