Frequently Asked Questions

You can place an order directly through our website by browsing our product catalog, adding items to your cart, and proceeding to checkout. Create an account or check out as a guest. For custom synthesis orders, use our online configurator tools or contact our team at info@bostonmolecules.com for a personalized quote.

You may also place orders by phone at (+1)-617-651-1016 or by emailing your order details to info@bostonmolecules.com.

Yes, we accept Purchase Orders (POs) from established institutional buyers, government agencies, universities, and approved corporate accounts. PO terms are Net 30 unless otherwise negotiated.

New institutional customers may need to complete a credit application before PO terms are extended. Please email your PO to orders@bostonmolecules.com or upload it during checkout.

We accept the following payment methods:

• Credit cards: Visa, MasterCard, American Express (processed securely via Braintree)
• Wire transfer and ACH
• Purchase Orders (for approved institutional buyers)

All transactions are conducted in US Dollars (USD).

There is no minimum order amount for catalog products. However, custom synthesis services have minimum quantity requirements that depend on the specific peptide or protein being synthesized. Our team can provide details when you request a quote.

Yes! We offer tiered pricing for bulk orders and long-term supply agreements. Volume discounts are available for both catalog products and custom synthesis services. Contact our sales team at info@bostonmolecules.com or use our Bulk Peptide Configurator to get an instant quote for larger quantities.

Z-Active® is our proprietary bioactive peptide technology platform developed by Boston Molecules. Z-Active® peptides are designed and optimized for enhanced biological activity, superior stability, and improved cell permeability compared to conventional peptide synthesis approaches.

This technology employs advanced sequence optimization, strategic modification placement, and rigorous quality control to deliver research-grade peptides with consistent, reproducible bioactivity. Visit our Z-Active® Technology page for more details.

We offer peptides at multiple purity levels to meet different research requirements:

• Crude (desalted): ~70% purity — suitable for antibody production and initial screening
• HPLC purified (>85%): Suitable for most in vitro assays
• HPLC purified (>90%): Recommended for quantitative studies
• HPLC purified (>95%): High purity for sensitive assays and structural studies
• HPLC purified (>98%): Ultra-high purity for critical research applications

Every peptide ships with a Certificate of Analysis (CoA) documenting purity by analytical HPLC and identity verification by mass spectrometry.

Yes, every product ships with a Certificate of Analysis (CoA). The CoA includes:

• Purity analysis (HPLC chromatogram)
• Identity confirmation (mass spectrometry data)
• Appearance and solubility information
• Lot number and manufacturing date
• Storage recommendations

CoAs are included with your shipment and can also be downloaded from your account dashboard or requested via email.

Crude (desalted) peptides have undergone basic purification to remove salts and reagents from synthesis but may contain truncated sequences and deletion peptides (typical purity ~70%). They are suitable for antibody production, ELISA coating, and initial experiments where high purity is not critical.

HPLC-purified peptides undergo reverse-phase high-performance liquid chromatography (RP-HPLC) to remove impurities, resulting in purities of 85–98%+. These are recommended for quantitative assays, cell-based studies, receptor binding experiments, and any application where consistent, reproducible results are essential.

Yes, all Boston Molecules products are sold strictly for Research Use Only (RUO). They are not intended for human or veterinary consumption, diagnostic, therapeutic, food, or cosmetic use. By purchasing our products, you confirm that they will be used exclusively for lawful in vitro research and laboratory experimentation.

Turnaround times depend on the complexity, length, and modifications of the peptide:

• Standard peptides (up to 30 amino acids, no modifications): 2–3 weeks
• Modified peptides: 3–4 weeks depending on the modification
• Long peptides (30–50+ amino acids): 4–6 weeks
• Complex modifications (cyclic, stapled, multiple modifications): 4–8 weeks

Rush synthesis services are available for an additional fee. Contact us for details.

Yes, we offer a wide range of peptide modifications including:

• N-terminal modifications: Acetylation, biotinylation, FITC/FAM labeling, PEGylation
• C-terminal modifications: Amidation, acid form
• Side-chain modifications: Phosphorylation (pSer, pThr, pTyr), methylation, citrullination
• Unnatural amino acids and D-amino acids
• Disulfide bridge formation
• Dye labeling and isotopic labeling

Use our Peptide Configurator tool for an instant quote, or contact us for complex or custom modifications.

Using standard Fmoc solid-phase peptide synthesis (SPPS), we routinely synthesize peptides up to 50 amino acids in length. For longer peptides (50–150 amino acids), we employ advanced techniques including native chemical ligation and fragment condensation to achieve successful synthesis.

For sequences exceeding 100 amino acids, we recommend considering our recombinant protein expression services as a cost-effective alternative. Contact us to discuss the best approach for your specific sequence.

Yes! We specialize in advanced peptide architectures including:

• Hydrocarbon stapled peptides using olefin metathesis
• Lactam bridge-stabilized peptides
• Disulfide-cyclized peptides
• Head-to-tail cyclic peptides
• Bicyclic and multi-cyclic peptides

Visit our Stapled Peptides and Cyclic Peptides pages for more information, or use our configurators for an instant quote.

Temperature-sensitive products such as recombinant proteins and certain peptides are shipped with appropriate cold chain packaging:

• Products requiring -20°C or -80°C storage are shipped on dry ice in insulated containers
• Products requiring 2–8°C storage are shipped with gel cold packs
• Lyophilized peptides stable at room temperature may ship at ambient conditions

We use expedited or overnight shipping for temperature-sensitive products to minimize transit time and ensure product integrity.

Yes, we ship to most countries worldwide via FedEx, UPS, and DHL. International shipping rates are calculated at checkout. Please note that customs duties, import taxes, and brokerage fees are the responsibility of the buyer.

Some products may be subject to export control regulations. We will notify you if any restrictions apply to your order.

Domestic (Continental US) shipping options:

• Standard: 3–5 business days
• Expedited: 1–2 business days
• Overnight: Next business day

International delivery typically takes 5–15 business days depending on destination and customs clearance. Orders are processed within 1–2 business days before shipping.

Yes! We offer free standard shipping on all domestic orders over $500. Orders under $500 are subject to a flat $50.00 shipping and handling fee for standard delivery. Expedited and overnight shipping costs are calculated at checkout.

Storage conditions vary by product type. Always refer to the product label and Certificate of Analysis (CoA) for specific storage instructions:

• Lyophilized Peptides: Store at -20°C desiccated. Stable at room temperature for short periods during handling. Reconstituted peptides should be aliquoted and stored at -20°C or -80°C.
• Recombinant Proteins: Store at -20°C or -80°C. Avoid repeated freeze-thaw cycles. Aliquot upon first use.
• Antibodies: Store at 2–8°C for short-term use or -20°C for long-term storage. Do not freeze aliquots in frost-free freezers.

Absolutely! Our team of PhD-level scientists is available to provide technical support for your research. We can assist with:

• Product selection and application guidance
• Peptide solubility and reconstitution advice
• Experimental design and troubleshooting
• Custom synthesis feasibility assessment
• Data interpretation and quality questions

Contact our technical support team at info@bostonmolecules.com or call (+1)-617-651-1016.

Yes, we provide protocol recommendations and application notes for many of our products. Our resources include:

• Peptide reconstitution and handling guides
• Recommended assay protocols (ELISA, Western blot, cell-based assays)
• Storage and stability guidelines
• Application-specific technical notes

Contact our technical team if you need a protocol recommendation specific to your experimental setup. We are happy to help optimize your workflow.