PT-141 / Bremelanotide

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SKU: BPT2920

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SKU: BPT2920-1MG $95.00
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PT-141 / Bremelanotide

Bremelanotide (PT-141) selectively activates MC3R/MC4R in the hypothalamus to modulate sexual desire via central dopaminergic stimulation. FDA-approved as Vyleesi® for hypoactive sexual desire disorder (HSDD) in premenopausal women. First centrally acting melanocortin-based sexual dysfunction therapeutic.

Product Specifications

CAS Number 189691-06-3
Molecular Weight 1025.18 Da
Molecular Formula C₅₀H₆₈N₁₄O₁₀
Purity Peak Area by HPLC ≥95%
Form Lyophilized
Storage -20°C
Usage Research use

Amino Acid Sequence

One-Letter Code:

Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-OH (cyclic)

Three-Letter Code:

Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH

Research Applications

  • Application: Receptor binding
  • Biomarker Target: Melanocortin Receptors (MC1-5R)
  • Research Area: Endocrinology
  • Sub-category: Melanocortin System & Pigmentation

Reconstitution & Storage

  • Reconstitution: Reconstitute in sterile water or appropriate buffer to desired concentration.
  • Storage: Store lyophilized product at -20°C. After reconstitution, aliquot and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
  • Stability: Lyophilized product is stable for 24 months when stored properly.

For research use only. Not for diagnostic or therapeutic use.

Bremelanotide (PT-141) selectively activates MC3R/MC4R in the hypothalamus to modulate sexual desire via central dopaminergic stimulation. FDA-approved as Vyleesi® for hypoactive sexual desire disorder (HSDD) in premenopausal women.

Safety Data Sheets & Documentation

Safety Data Sheet (SDS) PDF — BPT2920

Protocols & Support

Reconstitution Protocol

1. Briefly centrifuge the vial to collect lyophilized powder at the bottom.

2. Reconstitute in sterile deionized water or PBS to a concentration of 0.2–1.0 mg/mL.

3. Gently pipette up and down to dissolve. Do not vortex.

4. Aliquot and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.

Download Data Sheet

Complete product data sheet including batch-specific QC data, sequence information, and storage guidelines.

Download PDF Data Sheet