Custom Peptide Synthesis Services
Boston Molecules offers comprehensive custom peptide synthesis services, from standard linear peptides to complex modified, stapled, and cyclic peptides. Our state-of-the-art synthesis platform delivers high-purity peptides for research, drug discovery, and preclinical development.
Our Capabilities
| Service | Length | Purity | Scale |
|---|---|---|---|
| Standard Linear Peptides | 6–80 residues | ≥95%, ≥98% | 1 mg – 1 g+ |
| Modified Peptides | 6–60 residues | ≥95% | 1 mg – 500 mg |
| Stapled Peptides | 10–50 residues | ≥90%, ≥95% | 1 mg – 100 mg |
| Cyclic Peptides | 5–40 residues | ≥90%, ≥95% | 1 mg – 200 mg |
| Peptide Libraries | 6–30 residues | ≥70%, crude | 1 mg each |
Available Modifications
N-Terminal
- Acetylation (Ac-)
- Biotinylation
- FITC / FAM labeling
- PEGylation
- Fatty acid conjugation
C-Terminal
- Amidation (-NH2)
- Acid (-OH)
- Methylation
- Aldehyde
Backbone & Side Chain
- D-amino acids
- N-methylation
- Phosphorylation (pSer, pThr, pTyr)
- Disulfide bond formation
- Unnatural amino acids
Cyclization Strategies
- Head-to-tail — Backbone amide bond cyclization
- Disulfide bridge — Cysteine-Cysteine oxidation
- Lactam bridge — Side chain Lys-Glu/Asp linkage
- Thioether — Lanthionine-type cyclization
- Click chemistry (CuAAC) — Triazole linkage
- Hydrocarbon stapling (RCM) — Olefin metathesis
Quality Assurance
Every peptide is delivered with a comprehensive quality package:
- ✅ Certificate of Analysis (COA)
- ✅ RP-HPLC purity analysis
- ✅ Mass spectrometry (ESI-MS / MALDI-TOF) confirmation
- ✅ Amino acid analysis (upon request)
- ✅ Net peptide content determination
Typical Turnaround
| Peptide Type | Turnaround |
|---|---|
| Standard linear (≤20 aa) | 5–7 business days |
| Long peptides (20–50 aa) | 7–14 business days |
| Modified / labeled | 7–14 business days |
| Stapled / cyclic | 14–21 business days |
| Peptide libraries | 14–28 business days |
Get Your Custom Peptide Quote
Use our online configurator for an instant quote, or contact our team for complex projects.