Ac-Endothelin-1 (16-21), human

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SKU: BPT2612

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Ac-Endothelin-1 (16-21), human

Ac-Endothelin-1 (16-21), human is a 8-amino-acid A peptide from the endothelin family, one of the most potent vasoconstrictors known. Endothelins signal through ETA and ETB receptors to regulate vascular tone, cell proliferation, and fibrosis. Widely used in cardiovascular, pulmonary, and renal research for studying vasoconstriction, pulmonary hypertension, and the development of endothelin receptor antagonists.

Product Specifications

CAS Number 158884-64-1
Molecular Weight 837.9591 Da
Molecular Formula C₄₁H₅₉N₉O₁₀
Purity Peak Area by HPLC ≥95%
Form Lyophilized
Storage -20°C
Usage Research use

Amino Acid Sequence

One-Letter Code:

Ac-HLDIIW

Three-Letter Code:

Ac-His-Leu-Asp-Ile-Ile-Trp-OH

Research Applications

  • Application: Receptor binding
  • Biomarker Target: Endothelin Receptors (ETA/ETB)
  • Research Area: Cardiovascular
  • Sub-category: Endothelin System & Vasoconstriction

Reconstitution & Storage

  • Reconstitution: Reconstitute in sterile water or appropriate buffer to desired concentration.
  • Storage: Store lyophilized product at -20°C. After reconstitution, aliquot and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
  • Stability: Lyophilized product is stable for 24 months when stored properly.

For research use only. Not for diagnostic or therapeutic use.

Ac-Endothelin-1 (16-21), human is a 8-amino-acid A peptide from the endothelin family, one of the most potent vasoconstrictors known. Endothelins signal through ETA and ETB receptors to regulate vascular tone, cell proliferation, and fibrosis.

Safety Data Sheets & Documentation

Safety Data Sheet (SDS) PDF — BPT2612

Protocols & Support

Reconstitution Protocol

1. Briefly centrifuge the vial to collect lyophilized powder at the bottom.

2. Reconstitute in sterile deionized water or PBS to a concentration of 0.2–1.0 mg/mL.

3. Gently pipette up and down to dissolve. Do not vortex.

4. Aliquot and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.

Download Data Sheet

Complete product data sheet including batch-specific QC data, sequence information, and storage guidelines.

Download PDF Data Sheet