Amyloid β-Protein (4-42) ammonium salt/Aβ (4-42)

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SKU: BPT0012

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Amyloid β-Protein (4-42) ammonium salt/Aβ (4-42)

Amyloid β-Protein (4-42) ammonium salt/Aβ (4-42) is a 39-amino-acid A synthetic peptide fragment of the amyloid β-protein (Aβ), a 39–43 amino acid peptide that is the principal component of amyloid plaques in Alzheimer’s disease. This fragment is widely used in neuroscience research to study Aβ aggregation, neurotoxicity, and the molecular mechanisms underlying Alzheimer’s pathology. It serves as a valuable tool for investigating amyloid fibril formation, screening potential therapeutic agents, and elucidating structure-activity relationships within the Aβ sequence.

Product Specifications

CAS Number 157884-72-5
Molecular Weight 4198.7479 Da
Molecular Formula C₁₉₁H₂₉₄N₅₂O₅₃S₁
Purity Peak Area by HPLC ≥95%
Form Lyophilized
Storage -20°C
Usage Research use

Amino Acid Sequence

One-Letter Code:

FRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

Three-Letter Code:

H-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH

Research Applications

  • Application: Neurotoxicity & Aggregation
  • Biomarker Target: Amyloid-β / Tau
  • Research Area: Neuroscience
  • Sub-category: Neurodegeneration & Alzheimer’s Disease

Reconstitution & Storage

  • Reconstitution: Reconstitute in sterile water or appropriate buffer to desired concentration.
  • Storage: Store lyophilized product at -20°C. After reconstitution, aliquot and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
  • Stability: Lyophilized product is stable for 24 months when stored properly.

For research use only. Not for diagnostic or therapeutic use.

Amyloid β-Protein (4-42) ammonium salt/Aβ (4-42) is a 39-amino-acid A synthetic peptide fragment of the amyloid β-protein (Aβ), a 39–43 amino acid peptide that is the principal component of amyloid plaques in Alzheimer's disease. This fragment is widely used in neuroscience research to study Aβ a...

Safety Data Sheets & Documentation

Safety Data Sheet (SDS) PDF — BPT0012

Protocols & Support

Reconstitution Protocol

1. Briefly centrifuge the vial to collect lyophilized powder at the bottom.

2. Reconstitute in sterile deionized water or PBS to a concentration of 0.2–1.0 mg/mL.

3. Gently pipette up and down to dissolve. Do not vortex.

4. Aliquot and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.

Download Data Sheet

Complete product data sheet including batch-specific QC data, sequence information, and storage guidelines.

Download PDF Data Sheet