Big Endothelin -1 (1-39), porcine
Price range: $547.20 through $3,283.20
Big Endothelin -1 (1-39), porcine
Big Endothelin -1 (1-39), porcine is a 66-amino-acid A peptide from the endothelin family, one of the most potent vasoconstrictors known. Endothelins signal through ETA and ETB receptors to regulate vascular tone, cell proliferation, and fibrosis. Widely used in cardiovascular, pulmonary, and renal research for studying vasoconstriction, pulmonary hypertension, and the development of endothelin receptor antagonists.
Product Specifications
| CAS Number | 124932-61-2 |
| Molecular Weight | 4383.9667 Da |
| Molecular Formula | C₁₉₃H₂₈₉N₄₉O₅₈S₅ |
| Purity | Peak Area by HPLC ≥95% |
| Form | Lyophilized |
| Storage | -20°C |
| Usage | Research use |
Amino Acid Sequence
One-Letter Code:
CSCSSLMDKECVYFCHLDIIWVNTPEHIVPYGLGSPSRS(Disulfidebridge:Cys1-Cys15,Cys3-Cys11)
Three-Letter Code:
H-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-Val-Asn-Thr-Pro-Glu-His-Ile-Val-Pro-Tyr-Gly-Leu-Gly-Ser-Pro-Ser-Arg-Ser-OH(Disulfidebridge:Cys1-Cys15,Cys3-Cys11)
Research Applications
- Application: Receptor binding
- Biomarker Target: Endothelin Receptors (ETA/ETB)
- Research Area: Cardiovascular
- Sub-category: Endothelin System & Vasoconstriction
Reconstitution & Storage
- Reconstitution: Reconstitute in sterile water or appropriate buffer to desired concentration.
- Storage: Store lyophilized product at -20°C. After reconstitution, aliquot and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
- Stability: Lyophilized product is stable for 24 months when stored properly.
For research use only. Not for diagnostic or therapeutic use.
Safety Data Sheets & Documentation
Protocols & Support
Reconstitution Protocol
1. Briefly centrifuge the vial to collect lyophilized powder at the bottom.
2. Reconstitute in sterile deionized water or PBS to a concentration of 0.2–1.0 mg/mL.
3. Gently pipette up and down to dissolve. Do not vortex.
4. Aliquot and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
Download Data Sheet
Complete product data sheet including batch-specific QC data, sequence information, and storage guidelines.
Download PDF Data Sheet