[D-Arg1,D-Pro2,D-Trp7,9,Leu11]-Substance P

[D-Arg1,D-Pro2,D-Trp7,9,Leu11]-Substance P

[D-Arg1,D-Pro2,D-Trp7,9,Leu11]-Substance P is a 13-amino-acid A peptide related to the tachykinin/substance P family, an 11-amino-acid neuropeptide that signals through NK1 receptors to mediate pain transmission, inflammation, emesis, and neurogenic vasodilation. Widely used in pain, inflammation, and neuroscience research for studying nociception, neurogenic inflammation, and the development of NK1 receptor antagonists (e.g., aprepitant for chemotherapy-induced nausea).

Product Specifications

Amino Acid Sequence

One-Letter Code:

rpKPQQwFwLL-NH2

Three-Letter Code:

H-{D-Arg}-{D-Pro}-Lys-Pro-Gln-Gln-{D-Trp}-Phe-{D-Trp}-Leu-Leu-NH2

Research Applications

• Application: Receptor binding
• Biomarker Target: Neurokinin Receptors (NK1-3R)
• Research Area: Neuroscience
• Sub-category: Tachykinin Signaling & Pain

Reconstitution & Storage

• Reconstitution: Reconstitute in sterile water or appropriate buffer to desired concentration.
• Storage: Store lyophilized product at -20°C. After reconstitution, aliquot and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
• Stability: Lyophilized product is stable for 24 months when stored properly.

For research use only. Not for diagnostic or therapeutic use.

Safety Data Sheets & Documentation

Protocols & Support