Name: [Gly11] Substance P
Brand: Boston Molecules
SKU: BPT1934
Price: 51.85 USD
Availability: InStock

[Gly11] Substance P

[Gly11] Substance P is a 13-amino-acid A peptide related to the tachykinin/substance P family, an 11-amino-acid neuropeptide that signals through NK1 receptors to mediate pain transmission, inflammation, emesis, and neurogenic vasodilation. Widely used in pain, inflammation, and neuroscience research for studying nociception, neurogenic inflammation, and the development of NK1 receptor antagonists (e.g., aprepitant for chemotherapy-induced nausea).

Product Specifications

Molecular Weight	1273.4816 Da
Molecular Formula	C₆₀H₉₂N₁₈O₁₃
Purity	Peak Area by HPLC ≥95%
Form	Lyophilized
Storage	-20°C
Usage	Research use

Amino Acid Sequence

One-Letter Code:

RPKPQQFFGLG-NH2

Three-Letter Code:

H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Gly-NH2

Research Applications

Application: Receptor binding
Biomarker Target: Neurokinin Receptors (NK1-3R)
Research Area: Neuroscience
Sub-category: Tachykinin Signaling & Pain

Reconstitution & Storage

Reconstitution: Reconstitute in sterile water or appropriate buffer to desired concentration.
Storage: Store lyophilized product at -20°C. After reconstitution, aliquot and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
Stability: Lyophilized product is stable for 24 months when stored properly.

For research use only. Not for diagnostic or therapeutic use.

[Gly11] Substance P is a 13-amino-acid A peptide related to the tachykinin/substance P family, an 11-amino-acid neuropeptide that signals through NK1 receptors to mediate pain transmission, inflammation, emesis, and neurogenic vasodilation. Widely used in pain, inflammation, and neuroscience rese...