Larazotide

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SKU: BPT2912

Price range: $207.00 through $1,242.00

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SKU: BPT2912-1MG $207.00
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Larazotide

Larazotide acetate (AT-1001) is a first-in-class tight junction modulator for celiac disease. Zonulin receptor antagonist that blocks gluten-induced tight junction opening, maintaining epithelial barrier integrity. Advanced through Phase 2 clinical trials with symptomatic improvement.

Product Specifications

CAS Number 881851-50-9
Molecular Weight 785.89 Da
Purity Peak Area by HPLC ≥95%
Form Lyophilized
Storage -20°C
Usage Research use

Amino Acid Sequence

One-Letter Code:

Gly-Gly-Val-Leu-Val-Gln-Pro-Gly

Three-Letter Code:

H-Gly-{D-Leu}-{D-Tyr}-Gly-{D-Leu}-{D-Tyr}-Val-{D-Ala}-{D-Leu}-Leu-{D-Glu}-{D-Sec}-Val-{D-Ala}-{D-Leu}-Gly-{D-Leu}-{D-Asn}-Pro-{D-Arg}-{D-Pyl}-Gly-{D-Leu}-{D-Tyr}-OH

Research Applications

  • Application: Biological activity
  • Biomarker Target: Peptide Target
  • Research Area: Biomedical Research
  • Sub-category: Research Peptides & Tools

Reconstitution & Storage

  • Reconstitution: Reconstitute in sterile water or appropriate buffer to desired concentration.
  • Storage: Store lyophilized product at -20°C. After reconstitution, aliquot and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
  • Stability: Lyophilized product is stable for 24 months when stored properly.

For research use only. Not for diagnostic or therapeutic use.

Larazotide acetate (AT-1001) is a first-in-class tight junction modulator for celiac disease. Zonulin receptor antagonist that blocks gluten-induced tight junction opening, maintaining epithelial barrier integrity.

Safety Data Sheets & Documentation

Safety Data Sheet (SDS) PDF — BPT2912

Protocols & Support

Reconstitution Protocol

1. Briefly centrifuge the vial to collect lyophilized powder at the bottom.

2. Reconstitute in sterile deionized water or PBS to a concentration of 0.2–1.0 mg/mL.

3. Gently pipette up and down to dissolve. Do not vortex.

4. Aliquot and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.

Download Data Sheet

Complete product data sheet including batch-specific QC data, sequence information, and storage guidelines.

Download PDF Data Sheet