P21 (CNTF-derived)

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SKU: BPT2894

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SKU: BPT2894-1MG $162.00
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P21 (CNTF-derived)

P21 (P021) is a tetrapeptide mimetic derived from CNTF residues 148–151 with C-terminal adamantane for enhanced BBB permeability. Promotes neurogenesis and synaptic plasticity through BDNF upregulation. Studied in Alzheimer’s models for cognitive support. Orally bioavailable approach to CNTF-mediated neurotrophic signaling.

Product Specifications

CAS Number 1246751-68-7
Molecular Weight ~578.66 Da
Purity Peak Area by HPLC ≥95%
Form Lyophilized
Storage -20°C
Usage Research use

Amino Acid Sequence

One-Letter Code:

Ac-Asp-Gly-Gly-Leu-(adma)-NH₂

Research Applications

  • Application: Neuroprotection
  • Biomarker Target: Neurotrophic Factors
  • Research Area: Neuroscience
  • Sub-category: Neuroprotection & Cognitive Enhancement

Reconstitution & Storage

  • Reconstitution: Reconstitute in sterile water or appropriate buffer to desired concentration.
  • Storage: Store lyophilized product at -20°C. After reconstitution, aliquot and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
  • Stability: Lyophilized product is stable for 24 months when stored properly.

For research use only. Not for diagnostic or therapeutic use.

P21 (P021) is a tetrapeptide mimetic derived from CNTF residues 148–151 with C-terminal adamantane for enhanced BBB permeability. Promotes neurogenesis and synaptic plasticity through BDNF upregulation.

Safety Data Sheets & Documentation

Safety Data Sheet (SDS) PDF — BPT2894

Protocols & Support

Reconstitution Protocol

1. Briefly centrifuge the vial to collect lyophilized powder at the bottom.

2. Reconstitute in sterile deionized water or PBS to a concentration of 0.2–1.0 mg/mL.

3. Gently pipette up and down to dissolve. Do not vortex.

4. Aliquot and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.

Download Data Sheet

Complete product data sheet including batch-specific QC data, sequence information, and storage guidelines.

Download PDF Data Sheet