[Phe2, Nle4]-ACTH (1-24)

[Phe2, Nle4]-ACTH (1-24)

[Phe2, Nle4]-ACTH (1-24) is a 26-amino-acid A peptide related to the melanocortin system, derived from proopiomelanocortin (POMC) or its analogs. Melanocortins signal through MC1R-MC5R receptors to regulate pigmentation, inflammation, energy homeostasis, and sexual function. Used in dermatology, endocrinology, and neuroscience research for studying melanocortin receptor pharmacology and POMC processing.

Product Specifications

Amino Acid Sequence

One-Letter Code:

SFS{Nle}EHFRWGKPVGKKRRPVKVYP

Three-Letter Code:

H-Ser-Phe-Ser-{Nle}-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-OH

Research Applications

• Application: Receptor binding
• Biomarker Target: Melanocortin Receptors (MC1-5R)
• Research Area: Endocrinology
• Sub-category: Melanocortin System & Pigmentation

Reconstitution & Storage

• Reconstitution: Reconstitute in sterile water or appropriate buffer to desired concentration.
• Storage: Store lyophilized product at -20°C. After reconstitution, aliquot and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
• Stability: Lyophilized product is stable for 24 months when stored properly.

For research use only. Not for diagnostic or therapeutic use.

Safety Data Sheets & Documentation

Protocols & Support